Upward bound: follicular stem cell fate decisions

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Upward bound: follicular stem cell fate decisions.

Recent data suggest that heterogeneous compartments of the bulge display differential gene expression, and supply cells to different lineages within the pilosebaceous unit (Jaks et al, 2008; Jensen et al, 2009; Snippert et al, 2010). In particular, Lgr6 and Lrig1 are expressed above the CD34þ bulge region and Lgr6 expressing cells contribute primarily to the sebaceous gland (Figure 1). Thus, if...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 2011

ISSN: 0261-4189,1460-2075

DOI: 10.1038/emboj.2011.231